How Much Is Ketamine Treatment?

Short answer: IV ketamine infusions typically cost about $400 to $800 each, so a full initial course usually lands somewhere around $2,400 to $4,800. Spravato, the FDA-approved nasal spray, is priced very differently depending on insurance. Most IV ketamine is not covered by insurance, but FSA and HSA funds and financing can make it manageable. Here is the full breakdown, including exactly what we charge at Ketamine Uplift.

How much does IV ketamine cost?

Nationally, a single IV ketamine infusion usually runs about $400 to $800, with a median price near $450. Because the standard approach is a series rather than a one-off, most people are really budgeting for a course. A typical initial series of around six infusions, sometimes with maintenance sessions added, generally totals about $2,400 to $4,800.

IV ketamine for depression is considered off-label, so it is rarely covered by insurance. That sounds discouraging, but as you will see below, there are real ways to bring the cost down.

How much does Spravato cost?

Spravato (esketamine) is the one form of ketamine that the FDA has approved for depression, and that changes the math. With insurance, many patients pay only about $0 to $60 per visit, since Medicare and most major plans cover it with prior authorization. Without insurance, a Spravato visit including medication and monitoring can run roughly $900 to $1,300. So for people with coverage, Spravato can be the more affordable route, while for those paying cash, IV ketamine is often less expensive overall.

What affects the price?

A few factors explain most of the variation you will see between clinics:

• Location. Big coastal cities tend to cost more than smaller markets.

• Provider and setting. A physician-led clinic with private suites and close monitoring differs from a higher-volume, no-frills model.

• Number of infusions. More sessions means a higher total, though many clinics price a full course at a discount.

• What is included. Some prices bundle monitoring, follow-up, or integration support; others charge separately.

• Whether financing is offered. In-house payment plans can change what you actually pay month to month.

Is it covered by insurance?

Usually not for IV ketamine, and usually yes for Spravato. If insurance coverage is a priority, our guide to whether insurance covers ketamine and our breakdown of whether Blue Cross Blue Shield covers ketamine go through the details. One useful point for everyone: even when IV ketamine is not covered, it is generally FSA and HSA eligible, which lets you pay with pre-tax dollars.

What ketamine treatment costs at Ketamine Uplift

We keep our pricing transparent. The standard course is the eight-infusion Uplift Momentum Protocol, which includes twelve months of coverage, for $3,999. There are three ways to pay: $3,399 if you pay upfront, which is fifteen percent off; a Split-Pay option of $1,000 down and then $237 a month; or a Flexible plan of $333 a month for twelve months at zero percent interest. For people who completed an induction elsewhere and just want maintenance, a single infusion is $600, a four-pack is $2,200, and a six-pack is $3,000.

There is also a feature worth knowing about: if Dr. Geoffery O'Neill feels you need more than the standard six induction infusions to reach a breakthrough, he can extend the induction up to ten infusions at no additional cost. The course price stays the same, and the two planned boosters are already included. All plans are FSA and HSA eligible.

Making treatment affordable

Between FSA and HSA eligibility and our in-house financing, the goal is to keep cost from being the reason someone does not get help. And if an insurance-covered option matters to you, Spravato is coming soon to Ketamine Uplift, which most plans cover with prior authorization.

This article is for educational purposes only and is not medical or financial advice. Prices vary by provider and change over time; confirm current pricing directly.

The bottom line

Most IV ketamine treatment costs about $400 to $800 per infusion, or roughly $2,400 to $4,800 for a full course, and is rarely covered by insurance. Spravato is usually cheaper with insurance and pricier without. At Ketamine Uplift, the full eight-infusion course is $3,999, with upfront and financing options and FSA and HSA eligibility. If you want a clear, personalized estimate, call us at (310) 280-4440.

Frequently asked questions

How much does ketamine treatment cost?
IV ketamine infusions typically cost about $400 to $800 per session, with a median near $450. A full initial course usually totals around $2,400 to $4,800, depending on location, provider, and number of infusions.

How much is a full course of ketamine infusions?
A typical initial series is around six infusions, often followed by maintenance, which usually adds up to roughly $2,400 to $4,800 nationally. At Ketamine Uplift, the eight-infusion course with twelve months of coverage is $3,999.

Is ketamine treatment covered by insurance?
IV ketamine for depression is off-label and rarely covered. Spravato is covered by Medicare and most major plans with prior authorization. IV ketamine is generally FSA and HSA eligible.

How much does ketamine treatment cost at Ketamine Uplift?
The eight-infusion course is $3,999, or $3,399 upfront. Financing includes $1,000 down then $237 a month, or $333 a month for twelve months at zero percent interest. Single infusions are $600, a four-pack $2,200, and a six-pack $3,000.