Ketamine 101

Ketamine is FDA approved as an anesthetic, and esketamine (Spravato) is approved for treatment-resistant depression. Here is the full approval picture, including PTSD.

Ketamine infusion therapy delivers a low, controlled dose of ketamine by IV to treat depression, anxiety, and pain. Here is how it works and what a course looks like.

In a monitored medical setting, ketamine has a strong safety record built over 50 years. Here is an honest look at the risks, the safeguards, and who needs extra caution.

For many people with hard-to-treat depression, yes. Here is what the research shows about response rates, how fast it works, its limits, and who benefits most.

Yes, ketamine therapy is legal. Ketamine is an FDA-approved medication doctors can prescribe off-label for depression. Here is how that works and where Spravato fits.

A fair look at ketamine and addiction. In monitored, low-dose treatment for depression the risk is very low. Here is what the research shows and why supervision matters.

Ketamine went from a 1960s anesthetic to one of the biggest advances in depression care. Here is the surprising story, from the lab to the battlefield to today.

Ketamine-assisted psychotherapy pairs a monitored ketamine experience with preparation and integration therapy. Here is how KAP works and how it differs from a standard infusion.

IV ketamine and Spravato are both forms of ketamine for depression, but they differ in chemistry, how they are given, FDA approval, and insurance coverage. Here is how they compare.

Ketamine works differently from traditional antidepressants. It acts on the glutamate system to help the brain form new connections, which is why relief can arrive in hours rather than weeks.

Is ketamine really a horse tranquilizer? Will it knock you out? Is it addictive? We separate the most common ketamine therapy myths from the facts.

A clear, beginner-friendly guide to ketamine therapy: what it is, how it works in the brain, what it can treat, how it is given, and what to expect.